On January 6, 2021, the annual meeting of Ulanqab Kema new materials Co., Ltd. arrived as scheduled, and all the staff gathered together to count the details of our hard work in 2020. At the beginning of the annual meeting, Zhang Yu, chairman of the board
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On October 14-16, 2020, the 85th China international pharmaceutical raw materials / intermediates / packaging / Equipment Fair will be held in Nanjing International Expo Center. Kema company started construction in March 2018, put materials into trial ru
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In the face of difficulties, we went up against the wind and experienced the epidemic situation. We cherish our lives more, but we are never afraid. On December 16, 2020, Kema company made careful preparations. Mr. Zhang Yu, chairman of Kema new materials
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As we know, the use of each technology has several disadvantages. For example, the formation of salt is a complex process, in which the increase of solubility is not always predictable. This method is not suitable for neutral compound 37. As another examp
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Reducing the particle size and properties of the active ingredients or excipients is important in every stage of solid preparation manufacturing (micronization and transformation). The particle size affects the mixing, granulation, tableting, and coating
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The process of drug-dissolved molecules separating from the solid surface and entering the surrounding solution phase is called the dissolution process. Dissolution is a kinetic process that is usually controlled by diffusion.
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The preparations can be taken orally, parenterally, in the eyes, and in the lungs. Smaller particle sizes are required for rapid dissolution in the body or arterial uptake. However, slow-release or mononuclear macrophage targeting is better for larger par
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Through the method of preparing granular medicine, cortexin, a poorly soluble antioxidant, has the dissolution rate.
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Someone tried to improve the bioavailability and dissolution rate by preparing crystalline particles of 638.7nm-814.8nm. Under the premise of sodium lauryl sulfate as a stabilizer, anti-solvent precipitation technology is used.
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They found that the authors used spray drying to dry the crystals. It is inferred that the improvement of PRX dissolution is mainly attributed to another study. Lai and his colleagues used high-pressure homogenization and poloxamer 188 as a stabilizer to
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